成人弱视的流行病学研究进展 Recent advance in epidemiolgy of amblyopia in adult people 王越 [摘要] 成人弱视是成人视力损害的主要原因之一，由于不同国家和地区弱视筛查及诊断的视力标准不同，所得患病率也不同。本文对成人弱视的诊断标准，成人弱视的患病率，成人弱视的分类，形成弱视的危险因素，成人非弱视眼的视力损害风险，成人非弱视眼损害后对弱视眼的影响，成人弱视对接受教育和未来职业及生活的影响等方面进行综述。北京同仁医院眼科王越 [关键词] 弱视；成人；患病率；分类；非弱视眼
前言 弱视是危害人类视力和立体视觉的常见疾病，更是导致视力低下的主要原因，其防治的关键在于早期的视力筛查和早期治疗。在发达国家学龄前儿童视力筛查已经作为常规，而在发展中国家并没有开展全国性的普查，视力的筛查往往仅限于当地的医疗机构和小范围群体行为。以往国内弱视的研究往往集中于对学龄前儿童弱视的流行病学研究，筛查、诊断、和治疗，而对成人弱视的研究相对较少。弱视也是成年人单眼视力低下的常见原因，在the Beaver Dam眼病研究和the Blue Mountains 眼病研究中，弱视在成人单眼致盲因素中占据第三位。在邯郸眼病研究中，弱视在成人单眼盲中占第四位，在单眼低视力中占第二位因素。
参 考 文 献 [1]Ntim-Amponsah CT, Ofosu-Amaah S. Prevalence of refractive error and other eye diseases in schoolchildren in the Greater Accra region of Ghana. J Pediatr Ophthalmol Strabismus, 2007, 44: 294-297. 2.Klein R, Wang Q, Klein BE, et al. The relationship of age-related maculopathy, cataract, and glaucoma to visual acuity. Invest Ophthalmol Vis Sci 1995;36(1):182-91. 3.Attebo K, Mitchell P, Smith W. Visual acuity and the causes of visual loss in Australia. The Blue Mountains Eye Study. Ophthalmology 1996;103(3):357-64. 4.Liang YB, Friedman DS, Wong TY, et al. Prevalence and causes of low vision and blindness in a rural chinese adult population: the Handan Eye Study. Ophthalmology 2008;115(11):1965-72. 5.Holmes JM CM. Amblyopia. Lancet 2006;367:1343-51. 6.Gk VN, ed. Binocular vision and ocular motility:theory and management of strabismus, 4th ed. St Louis: CV Mosby, 1990; 208-13. 7.甘晓玲. 弱视的定义、分类及疗效评价标准. 中国斜视与小儿眼科杂志，1996，4（3）：97. 8.Holmes JM, Beck RW, Repka MX, et al. The amblyopia treatment study visual acuity testing protocol. Arch Ophthalmol 2001;119(9):1345-53. 9.Vinding T, Gregersen E, Jensen A, Rindziunski E. Prevalence of amblyopia in old people without previous screening and treatment. An evaluation of the present prophylactic procedures among children in Denmark. Acta Ophthalmol (Copenh) 1991;69(6):796-8. 10.Chua B, Mitchell P. Consequences of amblyopia on education, occupation, and long term vision loss. Br J Ophthalmol 2004;88(9):1119-21. 11.Attebo K, Mitchell P, Cumming R, et al. Prevalence and causes of amblyopia in an adult population. Ophthalmology 1998;105(1):154-9. 12.Brown SA, Weih LM, Fu CL, et al. Prevalence of amblyopia and associated refractive errors in an adult population in Victoria, Australia. Ophthalmic Epidemiol 2000;7(4):249-58. 13.Gilbert CE, Ellwein LB. Prevalence and causes of functional low vision in school-age children: results from standardized population surveys in Asia, Africa, and Latin America. Invest Ophthalmol Vis Sci 2008;49(3):877-81. 14.Negrel AD, Maul E, Pokharel GP, et al. Refractive Error Study in Children: sampling and measurement methods for a multi-country survey. Am J Ophthalmol 2000;129(4):421-6. 15.Rosman M, Wong TY, Koh CL, Tan DT. Prevalence and causes of amblyopia in a population-based study of young adult men in Singapore. Am J Ophthalmol 2005;140(3):551-2. 16.van Leeuwen R, Eijkemans MJ, Vingerling JR, et al. Risk of bilateral visual impairment in individuals with amblyopia: the Rotterdam study. Br J Ophthalmol 2007;91(11):1450-1. 17.Morad Y, Bakshi E, Levin A, et al. Screening and treating amblyopia: are we making a difference? Invest Ophthalmol Vis Sci 2007;48(5):2084-8. 18.Zhao J, Pan X, Sui R, et al. Refractive Error Study in Children: results from Shunyi District, China. Am J Ophthalmol 2000;129(4):427-35. 19.He M, Zeng J, Liu Y, et al. Refractive error and visual impairment in urban children in southern china. Invest Ophthalmol Vis Sci 2004;45(3):793-9. 20.Lu P, Chen X, Zhang W, et al. Prevalence of ocular disease in Tibetan primary school children. Can J Ophthalmol 2008;43(1):95-9. 21.王利华, 于秀敏, 刘丽萍, 等. 山东省10317名学龄前儿童弱视现状调查及疗效评价（第一部分：学龄前儿童弱视调查研究）.中国斜视与小儿眼科杂志，1996，4（3）：119-124. 22.Matsuo T, Matsuo C. The prevalence of strabismus and amblyopia in Japanese elementary school children. Ophthalmic Epidemiol 2005;12(1):31-6. 23.Drover JR, Kean PG, Courage ML, Adams RJ. Prevalence of amblyopia and other vision disorders in young Newfoundland and Labrador children. Can J Ophthalmol 2008;43(1):89-94. 24.Harvey EM, Dobson V, Clifford-Donaldson CE, Miller JM. Optical treatment of amblyopia in astigmatic children: the sensitive period for successful treatment. Ophthalmology 2007;114(12):2293-301. 25.Schmidt P, Maguire M, Dobson V, et al. Comparison of preschool vision screening tests as administered by licensed eye care professionals in the Vision In Preschoolers Study. Ophthalmology 2004;111(4):637-50. 26.Tommila V, Tarkkanen A. Incidence of loss of vision in the healthy eye in amblyopia. Br J Ophthalmol 1981;65(8):575-7. 27.Rahi J, Logan S, Timms C, et al. Risk, causes, and outcomes of visual impairment after loss of vision in the non-amblyopic eye: a population-based study. Lancet 2002;360(9333):597-602. 28.Rahi JS, Logan S, Borja MC, et al. Prediction of improved vision in the amblyopic eye after visual loss in the non-amblyopic eye. Lancet 2002;360(9333):621-2. 29.陈君平, 熊端华, 宋文喜. 青少年及成人弱视的治疗. 中国斜视与小儿眼科杂志，1997，5（4）：167-169. 30.Vereecken EP, Brabant P. Prognosis for vision in amblyopia after the loss of the good eye. Arch Ophthalmol 1984;102(2):220-4.
